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因拍摄上海第一套泳装台历的性感模特白玉兰圆睁双眼、身着泳装死于家中浴缸之内，圣约翰大学实验室女教授于胜男（李若斯 饰）、科学家康华生（徐亮 饰）、犯罪学专家洪小雅（马灿灿 饰）以及荣任探长的老孔联合展开调查。与此同时，坐镇巡捕房的总探长洪涛遭到炸弹袭击，险些丧命。总探长从康生等人的推理中察觉到，试图谋杀他的正是十年前涉嫌毒杀寡妇而亲手被他送入大牢的药房伙计何东来。十年前后两起案件，中药马钱子无疑都扮演了重要的角色，也因此一切线索似乎都指向了得到特赦的何东来。 扑朔迷离、吊诡猎奇的连环杀人案，以及隐藏长达十年的黑幕真相，一昔被揭开了面纱……。罗宾（玛丽·露易斯·帕克 Mary-Louise Parker 饰）患上了无法治愈的疾病，命不久矣。为了逃避现实，她决定踏上前往洛杉矶的旅途。简（乌比·戈德堡 Whoopi Goldberg 饰）一直以来都渴望成为一名歌手，无奈始终得不到机会，在机缘巧合之下，简成为了罗宾的司机，和她一同踏上旅程。 霍利（德鲁·巴里摩尔 Drew Barrymore 饰）是简的好友，在和男友发生了争执之后，霍利失手打伤了他，并且意外的导致了男友的死亡。身上背着一条人命的霍利选择和罗宾一行人一起远走高飞，在颠簸的旅途中，三个女人之间渐渐产生了坚实的友谊。罗宾的病越来越重，幸运的是，当她行走至人生的尽头时并不是孤身一人。。Vishal (Ajay Devgan), a stock analyst, and his wife Swati (Urmila Matondkar). The two are in search for a flat in Mumbai. Vishal finds the perfect place on the 12th floor of a high-rise apartment building. However, the apartment has a horrifying past. The previous occupant of the flat, a young woman had killed her child and jumped from the balcony and died. Swati learns about this incident shortly after moving in and becomes oddly fixated with the story. Then, a series of inexplicable experiences drive Swati to near madness. Vishal becomes helpless and convinced his wife has developed some sort of psychological disorder. He consults a psychiatrist, Dr. Rajan (Victor Banerjee). The couple's maid (Seema Biswas) believes Swati to be possessed, and calls in an exorcist (Rekha). Meanwhile, other seemingly unrelated events take place around the building. The watchman (Sabeer Masani) is being terrorized, one of the residents Sanjay (Fardeen Khan) is behaving erratically, and a murder occurs. Inspector Liaqat Quereshi (Nana Patekar) is sent to investigate the murder at the building. All the while, neither the psychiatrist nor the exorcist makes much progress with Swat。